Keywords
Corneal Perforation on Interferon Therapy
Squamous Cell Carcinoma Perforation
OSSN
How to Cite
Abstract
Squamous cell carcinomas of the cornea are rare tumours. After excision, adjuvant treatment in the form of topical Interferon is commonly used to prevent recurrences and also for margin positive excisions. Ours is a chronic hepatitis B patient who underwent excisional biopsy and presented as corneal perforation while on topical adjuvant Interferon therapy. It can be secondary to previous surgery or unusual presentation, such as tumour perforation. The secondary role of initiating IFN therapy causing perforation is a possibility, and the complication needs to be assessed further. It may be prudent to avoid interferon drops in patients with compromised ocular surface tectonic stability and immune-compromised individuals. Plaque brachytherapy would be a better adjuvant in these cases.
References
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