Abstract
Schwannomas are benign tumors arising from Schwann cells, typically found in peripheral nerves. Their occurrence in the nasal cavity is rare.We present the case of a 60-year-old female with a gradually enlarging mass in the left nasal cavity, ultimately causing complete obstruction. The rhinolological examination revealed a round mass, confirmed by CT and MRI. Endoscopic resection was performed, and histopathological analysis confirmed a benign Antoni type A schwannoma. This case emphasizes the importance of including schwannomas in the differential diagnosis of nasal masses. Endoscopic resection proved effective for complete removal, with no complications. The findings align with existing literature on the rarity of nasal schwannomas, their clinical presentation, and the significance of thorough postoperative follow-up. Nasal schwannomas are rare tumors that can cause significant nasal obstruction. Early diagnosis and complete surgical excision via an endoscopic approach are critical for favorable outcomes.
References
Liao JY, Lee HS, Kang BH. Nasal cavity schwannoma: A case report and review of the literature. Ear Nose Throat J. 2021;1-6.
Seles FM, Srinivasan P, Ramadoss N. Schwannoma nasal cavity: A clinicopathological case report. Int J Otorhinolaryngol Head Neck Surg. 2019;5:781-4.
Yoshida H, Adachi T, Nishi H, Kitaoka K, Kumai Y. Sphenoid sinus schwannoma with adhesion to the carotid canal. Radiology Case Reports 2023 ;18 (5) : 2019-2023.
Min HJ, Hong SC, Kim KS. Nasal septal schwannoma: Advances in diagnosis and treatment. J Craniofac Surg. 2017;28(1):97-101.
Nascimento LA, Settanni FA, Filho JF, Sanchez IN, Cavalcante BB, Stavale JN. Isolated schwannoma of the olfactory groove: A case report. Int Arch Otorhinolaryngol. 2015;19(1):93-95.
Nasal septum schwannoma: A rare clinicopathological case report in an 18-year-old female. Int J Appl Basic Med Res. 2022;12(4):284–287.
Cakmak O, Yavuz H, Yucel T. Nasal and paranasal sinus schwannomas. Eur Arch Otorhinolaryngol; 2003; 260, 195–197.
Wang LF, Tai CF, Ho KY, Kuo WR, Chai CY. Schwannoma of the nasal septum: A case report; Kaohsiung J Med Sci;2004;20:142-5.
Min HJ, Kim KS. Differential diagnosis between nasal septal schwannoma and nasal septal neurofibroma. J Craniofac Surg. 2017;28:1780-3.
Berlucchi M, Piazza C, Blanzuoli L, Battaglia G, Nicolai P. Schwannoma of the nasal septum: A case report with review of the literature; Eur Arch Otorhinolaryngol; 2000;257:402-5.
Venkatasamy R, Singh AS, Arasu K, Husain S, Mianxin C. Nasal septal ancient schwannoma: Ancient and rare; Cureus; 2023;15(8):e44294
Liao JY, Lee HS, Kang BH. Nasal cavity schwannoma—A case report and review of the literature. Ear Nose Throat J. 2024;103(1):19-24.
Freeman E, Hecht L, Crum J, Lutz M. Anterior nasal schwannoma: A rare sinonasal neoplasm. Cureus. 2023;15(7):e41300.
Maniglia AJ, Chandler JR, Goodwin WJ Jr, Parker JC Jr. Schwannomas of the parapharyngeal space and jugular foramen. Laryngoscope. 1979;89:1405–14.
Barati B, Mohseni M, Asadi M, Mangeli F. Schwannoma of the lateral nasal wall: A case report. Clin Case Rep. 2022;10:e05451.
Facon F, Forman C, Paris J, Chapon F, Moulin G, Dessi P. Le schwannome du septum nasal. A propos d'un cas [A case of nasal septum schwannoma: endoscopic resection]. Ann Otolaryngol Chir Cervicofac. 2004;121(3):179-83.
Devaraja K, Nayak DR, Ramaswamy B, Rao P. Nasal septal schwannoma: A rare sinonasal tumour with certain peculiarities. BMJ Case Rep. 2018 ; 18:bcr2017223850

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